Monocinnamic ester of glycerin.



UNHIE- sre rns re GERMANY, ASSIGNOB TO FA RBENFABRIKEN VORM.

Jtl'RGEN CALLSEN, OF ELBERFELD,

E sa rati FRIEDR. BAYER & (10., OF ELBERFELD, GERMANY, A GOEPOEATTON 0F GERMANY.

MONOCINNAMIC ESTER OF GLYGERIN:

No Drawing.

' To all whom it may concern:

Be it known that 1, Jones}: CALLSEN, doctor of philosophy, chemist, citizen of the German Empire, residing at Elberteld, Germany, have invented new and useful 1mprovements in lllonocinnamic Ester of Glycerin, of which the following is a specification.

I have found that the new mono-cinnamic ester of glycerin can be obtained by esterification of cinnamic acid with glycerin. The new ester has proved to be an excellent remedy against scabies. It possesses the advantage over leru balsam hitherto used for this purpose that itis odorless, non-irritant and easily soluble.

In order to illustrate the new process more fully the following example is given, the parts being by weight-148 parts of cinnamic acid are heated with 400 parts of glycerin and parts of concentrated suluric acid (60 B6.) in an oil bath during 60 hours to 140 C. The melt is then extracted with ether and the ethereal solution- Specification of Letters Patent. Ap olieation filed May 2, 1911. Serial No. 624,598.

Fatented Aug. 8. 1911,

is shaken with soda solution until it, shows a slightly alkaline reaction. The ethereal solution is then dried, the ether is removed and the residue distillo n vacuo. The ester thus obtained is a yello= h oil soluble in alcohol, ether and ehloro: r v

I claim The herein described ester of the formula erin cinnamie remedy against scabies, substantially as dewhich is a yellowish oil scribed.

In testimony whereof I have hereunto set my hand in the presence of two subscribing witnesses.

June-EN CALLSEN.

WVitne sses:

CHAS. J. VVnierrr, ALFRED HnNKnL. 

